calcineurin

calcineurin
Calmodulin-stimulated protein-phosphatase (EC 3.1.3.16), the major calmodulin-binding protein in brain. Enzymic activity is inhibited by binding of immunophilin-ligand complex (immunophilin alone does not bind) and therefore may play a part in the mechanism of action of cyclosporin A and FK506. Thought also to be involved in the control of sperm motility.

Dictionary of molecular biology. 2004.

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  • Calcineurin — Bändermodell des Heterodimer Aα+B1 (von oben/frontal) nach PDB  …   Deutsch Wikipedia

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  • calcineurin — noun A protein phosphatase that stimulates the growth and differentiation of T cells …   Wiktionary

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  • CABIN1 — Calcineurin binding protein 1, also known as CABIN1, is a human gene.cite web | title = Entrez Gene: CABIN1 calcineurin binding protein 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=23523| accessdate =… …   Wikipedia

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